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Laboratories

Aiming for pharmacists as high level medical personnel, through the latest pharmaceutical research which develops healthcare

Pharmacy is a comprehensive science of life, involving the lives and health of people. Not only research on drugs including pharmaceutics are conducted, as well as research on intractable diseases, but research for the future of medicine as members of a medical team is ongoing in each laboratory.

  • Pharmaceutical Research Laboratory

    Laboratory of BiopharmaceuticsProfessor Shinji YAMASHITA

    Translational research for development of oral drug products having high efficacy and safety

    Oral drug products are most friendly to patients, no pain, easy to take, however, there are many drugs which do not show sufficient therapeutic effects after oral administration, due to the low absorption from the gastrointestinal tract. Biopharmaceutics laboratory, collaborating with many pharmaceutical companies in the world, has continued the research for gastrointestinal absorption of drugs, including insulin and other bio-medicines, to develop efficient and safe products for oral use,

    Research themes
    (examples)
    • Improvement of Oral absorption of poorly soluble drugs using Supersaturation
    • Analysis of drug absorption and disposition in the body using molecular imaging technology
     Professor Shinji SAKUMA

    We are focusing on Drug Delivery System

    Absorption, distribution, metabolism, and elimination of drugs administered into human bodies depend on their intrinsic properties. Drug delivery system (DDS) is pharmaceutics- and medicinal chemistry-based technologies that optimize the destinies of drugs in bodies. Based on functional polymers, we are investigating new drugs and novel drug delivery systems that control the performance of drugs at the mucosa of the intestine, nasal cavities, etc. We recently succeeded to obtain a nano-bioconjugate that detects colorectal cancer on the mucosal surface of the large intestine. This study is under collaboration with the Japanese company and the university in the U.S.A.

    Research Themes
    (examples)
    • Development of contrast agents for endoscopy that enable physicians to diagnose the colorectal cancer in the early stage
    • Development of cell-penetrating peptides-linked polymers that enhance the membrane permeation of nucleic acids and proteins with poor membrane permeability
  • Pharmaceutical Chemistry Laboratory

    Laboratory of Pharmaceutical ChemistryProfessor Akira Ando

    Developing new drugs utilizing fluorine to enhance the efficacy of the drug

    Fluorine is used in many pharmaceuticals, and is not limited to familiar products such as fluoridated toothpaste and fluorine coating. Introducing fluorine into an organic compound which functions as a drug has various effects, such as increasing the rate of absorption in the body and sustaining the effects. In our laboratory we are conducting research and development on methods of introducing it. Recently, we have succeeded in introducing fluorine into an antibiotic. We are now proceeding to the next step, the evaluation phase.

    Research Themes
    (examples)
    • Research on the asymmetric synthesis of fluorine-containing β-lactam
    • Reductive Reformatsky-Honda reaction of α, β-unsaturated esters
  • Microbiology Laboratory

    Laboratory of MicrobiologyAssociate Professor Hiromu Takamatsu

    Studying the wide variety of microorganisms on the earth, and contributing to health improvement

    A wide variety of bacteria are present on the earth, some of which are closely connected with the life of human beings. Among those related to health are pathogenic bacteria, such as those that cause infections. At our laboratory we conduct research on genes and cell structures which have resistance to sterilization processes. In addition, we are also studying ways of quickly verifying the results of killing bacteria with heat or antimicrobial agents in cooperation with corporate researchers.

    Research Themes
    (examples)
    • Analysis of the germination mechanism of Bacillus subtilis cells
    • Fluorescence microscope observation of Staphylococcus aureus damaged by antibiotics
  • Pharmaceutical Research Laboratory

    Laboratory of BiopharmaceuticsProfessor Shinji YAMASHITA

    Translational research for development of oral drug products having high efficacy and safety

    Oral drug products are most friendly to patients, no pain, easy to take, however, there are many drugs which do not show sufficient therapeutic effects after oral administration, due to the low absorption from the gastrointestinal tract. Biopharmaceutics laboratory, collaborating with many pharmaceutical companies in the world, has continued the research for gastrointestinal absorption of drugs, including insulin and other bio-medicines, to develop efficient and safe products for oral use,

    Research themes (examples)
    • Improvement of Oral absorption of poorly soluble drugs using Supersaturation
    • Analysis of drug absorption and disposition in the body using molecular imaging technology
  • Pharmaceutical Research Laboratory

    Laboratory of BiopharmaceuticsProfessor Shinji SAKUMA

    We are focusing on Drug Delivery System

    Absorption, distribution, metabolism, and elimination of drugs administered into human bodies depend on their intrinsic properties. Drug delivery system (DDS) is pharmaceutics- and medicinal chemistry-based technologies that optimize the destinies of drugs in bodies. Based on functional polymers, we are investigating new drugs and novel drug delivery systems that control the performance of drugs at the mucosa of the intestine, nasal cavities, etc. We recently succeeded to obtain a nano-bioconjugate that detects colorectal cancer on the mucosal surface of the large intestine. This study is under collaboration with the Japanese company and the university in the U.S.A.

    Research Themes (examples)
    • Development of contrast agents for endoscopy that enable physicians to diagnose the colorectal cancer in the early stage
    • Development of cell-penetrating peptides-linked polymers that enhance the membrane permeation of nucleic acids and proteins with poor membrane permeability
  • Pharmaceutical Chemistry Laboratory

    Laboratory of Pharmaceutical ChemistryProfessor Akira Ando

    Developing new drugs utilizing fluorine to enhance the efficacy of the drug

    Fluorine is used in many pharmaceuticals, and is not limited to familiar products such as fluoridated toothpaste and fluorine coating. Introducing fluorine into an organic compound which functions as a drug has various effects, such as increasing the rate of absorption in the body and sustaining the effects. In our laboratory we are conducting research and development on methods of introducing it. Recently, we have succeeded in introducing fluorine into an antibiotic. We are now proceeding to the next step, the evaluation phase.

    Research Themes (examples)
    • Research on the asymmetric synthesis of fluorine-containing β-lactam
    • Reductive Reformatsky-Honda reaction of α, β-unsaturated esters
  • Microbiology Laboratory

    Laboratory of MicrobiologyAssociate Professor Hiromu Takamatsu

    Studying the wide variety of microorganisms on the earth, and contributing to health improvement

    A wide variety of bacteria are present on the earth, some of which are closely connected with the life of human beings. Among those related to health are pathogenic bacteria, such as those that cause infections. At our laboratory we conduct research on genes and cell structures which have resistance to sterilization processes. In addition, we are also studying ways of quickly verifying the results of killing bacteria with heat or antimicrobial agents in cooperation with corporate researchers.

    Research Themes (examples)
    • Analysis of the germination mechanism of Bacillus subtilis cells
    • Fluorescence microscope observation of Staphylococcus aureus damaged by antibiotics

Other Seminars

  • Laboratory of Pharmacognosy
    Basic research for drug development is conducted targeting herbal and medicinal plants, ethnic medicines and Chinese medicine, separating the medicinal components and determining their chemical structure.
  • Laboratory of Natural Product Chemistry
    A variety of natural products ranging from plants to insects are studied in order to discover substances that can be sources of new drug development.
  • Laboratory of
    Pharmaceutical Physicochemistry
    Exploring ways to improve the disadvantages of new and existing drugs and new methods of administration, to research formulations by which drugs can be used most effectively.
  • Laboratory of Clinical Analytical Chemistry
    Research is conducted to establish analytical chemistry techniques for quantitatively assessing the risk of cancer metastasis, and to develop metastasis inhibitors and supplements.
  • Laboratory of Biochemistry
    Research is carried out with the aim of developing new anticancer drugs which target growth factor receptors.
  • Laboratory of Public Health & Preventive Pharmacology
    Physiological and biochemical mechanisms of essential trace elements such as selenium are being studied, which are useful in prevention of oxidative stress or immune abnormality-related diseases.
  • Laboratory of Environmental Health
    Preventive research for human illness induced by interaction between the surplus or lack of nutrition and the food contaminant.
  • Laboratory of Toxicology
    The process whereby chemicals show toxicity in the body, and the kinds of interactions they have with proteins, nucleic acids, etc. are clarified.
  • Laboratory of Pharmacology
    We have 2 topics as research projects. One is to elucidate the mechanism underlying enhancement of neurogenesis after neuronal loss in brain. Other is to elucidate the mechanism underlying sensorineural hearing impairment and to develop preventive medicines and therapeutic medicines for the hearing impairment.
  • Laboratory of Pharmacotherapeutics
    The pathogenic mechanism of neurodegenerative disease such as Parkinson's disease and amyotrophic lateral sclerosis are elucidated, with the aim of developing therapeutic agents.
  • Laboratory of Clinical Pharmaceutics
    Research is conducted on effective and safe use of drugs as xenobiotics.
  • Laboratory of Medical Pharmacy
    Conducting the analysis of prescription required of a pharmacist, diseases and proper prescription are considered and researched from the viewpoint of clinical pharmacology and pharmaceutics.
  • Laboratory of Pathological Biochemistry
    Research is carried out on the origin and prevention of allergic disorders and autoimmune diseases and the development of effective treatments, with a view to clinical practice.
  • Laboratory of Pathology
    Side effects of drugs under development and existing drugs are examined using experimental animals. The pathology analysis is also conducted using animal models of human disease.
  • Laboratory of Pharmaceutical Education
    Research is conducted on methods of education and evaluation suitable for the Faculty of Pharmaceutical Sciences. The research effectively supports pharmaceutical education at the school.

Teaching Staff and Expertise

Dean
Kiyokazu OGITA

Department of Pharmaceutical Sciences

◆Department Chair: Takeyuki KONO

PositionNameDegreeArea of expertisePrimary subjectsRemarks
Professor AKIZAWA Toshifumi Ph.D. Clinical analysis / Protein chemistry Clinical Analysis
ANDO Akira Ph.D. Pharmaceutical chemistry / Organofluorine chemistry Organic Chemistry I
UENO Hitoshi Ph.D. Public health Public Health Science II
OHTA Souichi Ph.D. Environmental health / Food hygienics Food Hygienic Science I
OTSUKA Masato Ph.D. Biochemistry / Clinical biochemistry / Structural biology Molecular Cell Biology I
OGITA Kiyokazu Ph.D. Neuropharmacology Pharmacology
KONO Takeyuki Ph.D. Pathological biochemistry / Immunology Immunology
SAKUMA Shinji Ph.D. Pharmaceutics / Drug delivery system (DDS) Physical Pharmacy
SONE Tomomichi Ph.D. Drug metabolism Biopharmacy
NAKANISHI Kunio Ph.D. Pharmaceutics Understanding of Prescription
NODA Naoki Ph.D. Natural products chemistry / Instrumental analysis Instrumental Analysis I
HASHIMOTO Naofumi Ph.D. Physical pharmacy / Pharmacy Physical Chemistry I
HANE Yumiko   Clinical pharmacy Low in Parmaceutical Fields
FUJIMORI Hiroyuki Ph.D. Biochemistry / Toxicology English for Pharmacist II
MAEDA Sadaaki Ph.D. Pharmacotherapeutics / Molecular pharmacology Pharmacotherapeutics II
YABE Takeshi Ph.D. Chinese medicine Introduction to "kanpo" Prescription
YAMASHITA Shinji Ph.D. Pharmaceutics Pharmacokinetics and Dynamics
YAMAMOTO Toshiko   Clinical pharmacy Pre-training of Clinical Pharmacy
Associate professor IMAI Kimie Ph.D. Clinical pharmaceutics Hospital Pharmacy
OMOTE Masaaki Ph.D. Pharmaceutical chemistry / Organofluorine chemistry Organic Chemistry III
KATAKAWA Junichi Ph.D. Drug synthesis / Physical and chemical properties Basic Laboratory Practice
KIMURA Tomoki Ph.D. Toxicology / Molecular biology Radiobiology
KURAMOTO Nobuyuki Ph.D. Neuropharmacology Anatomy and Physiology I
KONISHI Motomi Ph.D. Clinical analysis chemistry / Natural products chemistry Principles of Pharmacopoeia
SHUTO Makoto Ph.D. Clinical pharmacy Introduction to OTC Drug
TAKADA Masahiro Ph.D. Clinical pharmacy Social Pharmacy
TAKAMATSU Hiromu Ph.D. Microbiology Infectious Diseases
NAKAMURA Mitsutaka Ph.D. Pathological physiology Pathological Physiology
MATSUURA Tetsuro Ph.D. Embryology Fundamental Practice II
(Biology)
YASUHARA Tomohisa Ph.D. Pharmaceutical education Medicinal Chemistry
Lecturer OKUNO Tomofumi Ph.D. Public health Public Health Science I
OZAKI Kiyokazu Ph.D. Pathology Basic Laboratory Practice
KIKUTA Maho Ph.D. Clinical pharmacy Pre-training of Clinical Pharmacy
KOMORI Koji Ph.D. Clinical pharmacy Pre-training of Clinical Pharmacy
TAKEUCHI Kenji Ph.D. Molecular biology / Biochemistry Biochemistry I
TSUJI Takumi Ph.D. Immunology / Pathological biochemistry Pathological Biochemistry
TOMURA Kaoru Ph.D. Mathematical physical chemistry / Medical engineering English for Pharmacist I Laboratories HP
NAKAO Teruyuki Ph.D. Environmental health / Food hygienics Food Hygienic Sciences II
NAKATANI Takafumi Ph.D. Natural product chemistry Natural Product Chemistry
YANADA Kazuo Ph.D. Biophysics / History of science and technology Physics
YOSHIOKA Yasuhiro Ph.D. Pharmacotherapeutics / Neuropharmacology Pharmacotherapeutics IV
YONEYAMA Masanori Ph.D. Neuropharmacology Advanced Medical Sciences I
Assistant professor AKIYAMA Ema   Environmental health / Molecular biology Laboratory Practice of Hygienic Pharmacy
ARAKAWA Tomohiro Ph.D. Public health Laboratory Practice of Hygienic Pharmacy
ARAKI Ryota Ph.D. Pharmacognosy Laboratory Practice of Basic Pharmacy I
ISIMARU Yuki Master
(Pharmacology)
Pharmacotherapeutics Laboratory Practice of Clinical Pharmacy
INATOMI Yuka Ph.D. Pharmacognosy Laboratory Practice of Basic Pharmacy I
IWAZAKI Ayano Ph.D. Biosystem pharmacy Basic Laboratory Practice
OGINO Hirohumi   Public health Laboratory Practice of Hygienic Pharmacy
KAKUTANI Hideki Ph.D. Environmental health / Immunology Laboratory Practice of Hygienic Pharmacy
KATAOKA Makoto Ph.D. Pharmaceutics Laboratory Practice of Clinical Pharmacy
KUWANA Ritsuko Ph.D. Molecular biology / Microbiology Laboratory Practice of Basic Pharmacy II
GODA Mitsuhiro Ph.D. Biochemistry Laboratory Practice of Basic Pharmacy II
SATO Kazuyuki Ph.D. Pharmaceutical chemistry / Organic chemistry Laboratory Practice of Basic Pharmacy I
SHIBA Tatsuo   Pharmacology Laboratory Practice of Clinical Pharmacy
TANAKA Ryuichiro Ph.D. Natural products chemistry Laboratory Practice of Basic Pharmacy I
TANIGUCHI Masanari Ph.D. Clinical analysis Laboratory Practice of Basic Pharmacy II
TARUI Atsushi Ph.D. Pharmaceutical chemistry / Organofluorine chemistry Laboratory Practice of Basic Pharmacy I
NAKANO Shoko   Clinical pharmacy Pre-training of Clinical Pharmacy
HOSAKA Takuomi Ph.D. Toxicology Laboratory Practice of Hygienic Pharmacy
MITAMURA Shinobu   Clinical pharmacy Pre-training of Clinical Pharmacy
MIYAZAKI Tamami   Clinical pharmacy Pre-training of Clinical Pharmacy
YAMAGUCHI Taro   Pharmacology Laboratory Practice of Clinical Pharmacy
YUMINOKI Kayou   Physical pharmacy Basic Laboratory Practice
YOSHIDA Yuya   Immunology / Pathological biochemistry Practical Exercise of Clinical Pharmacy
Research Associate AIZAWA Hideki     Laboratory Practice of Clinical Pharmacy
KURIO Wasako   Pharmaceutical education Basic Laboratory Practice
NISHIKAWA Tomoe   Pharmaceutical education Basic Laboratory Practice
MASAOKA Yoshie   Pharmaceutics Laboratory Practice of Clinical Pharmacy
MURATA Hiroko   Pharmaceutical botany Laboratory Practice of Basic Pharmacy I
YAMAMURO Akiko   Pharmacotherapeutics Practical Exercise of Clinical Pharmacy
YAMAMOTO Yumi   Pharmaceutical education Basic Laboratory Practice

Faculties

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