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 Reference


Regioselective synthesis of methylated epigallocatechin gallate vianitrobenzenesulfonyl (Ns) protecting group
Yoshiyui Aihara, Atsusi Yoshida, Takumi Furuta, Toshiyuki Wakimoto, Toshifumi Akizawa, Motomi Konishi and Toshiyuki Kan
Bioorganic & medicinal Chemistry Letters, Vol.19, Issue15, 4171-4174, 1 Aug 2009

Anti-angiogenic effect of green tea catechin through inhibition of membrane-type 1 matrix metalloproteinase, MT1-MMP

Kosuke Shimizu, Toshifumi Akizawa, Tomohiro Asai and Naoto Oku

Beneficial Health Effects of Green Tea, 2008: 41-50

Characterization of a novel metalloproteinase in Duvernoy's glamd of Rhabdophis tigrinus tigrinus
Koji Komori, Motomi Konishi, Yuji Maruta, Michihisa Toriba, Atsushi Sakai, Akira Matsuda, Takamitsu Hori, Mitsuko Nakatani, Naoto Minamino and Toshifumi Akizawa
J Toxicol Sci. Vol.31, No.2, 157-168, 2006

(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis
S. Yamakawa, T. Asai, T. Uchida, M. Matsukawa, T. Akizawa, N. Oku
Cancer letters, 210, 47-55, 2004

Purification of a Metalloproteinase in the Duvernoy's Glands of Rhabdophistigrinus by Affinity Column based on Cysteine Switch Mechanism
K. Komori, M. Konishi, T. Hori, M. Toriba, A. Sakai, T. Akizawa
Peptide Science 2003, 477-480, 2004

Amino Acid Sequence as Specific Peptide Substrate Targeted Membran-Type 1 Matrix Metalloproteinase
R. Iemura, M. Konishi, M. Yamada, H. Suzuki, Y. Suma, T. Akizawa 
Peptide scienece 2003 , 399-342, 2004  

Finding of the chaperone peptide
Aya Kojima, Motomi Konishi, Masatoshi Nishi, and Toshifumi Akizawa
Peptide Science2008, 277-280, 2009

Novel digitalis-like factor, marinobufotoxin,isolated from cultured Y-1 cell ,and its hypertensive effect in rats
M. Yoshioka, Y. Komiyama, M. Konishi, T. Akizawa, T.kobayashi, M.Date, S. Kobatake, M. Masuda, H. Masaki, H. Takahashi
Hypertension, 49, 209-214, 2007

Blood Pressure-Depressing Activity of a Peptide Derived from Silkworm Fibroin in Spontaneously Hypertensive Rats
Kiharu Igarashi, Kosuke Yoshioka, Kenji Mizutani, Masazumi Miyakoshi, Toshiyuki Murakami and Toshifumi Akizawa
Biosci.Biotechnol.Biochem., 70(2), 517-520, 2006

Engineering expression of bacterial polyphosphate kinase in tobacco for mercury remediation

Takeshi Nagata . Masako Kiyono . Hidemitsu Pan-Hou

Appl. Microbiol. Biotechnol. 2006 72(4) 777-782


Involvement of Aromatic Amino Acids in Phenylmercury Transport by MerT Protein

Takeshi Nagata . Masako Kiyono . Hidemitsu Pan-Hou

Journal of Health Science. 2006 52(4) 475-477 


Engineering expression of polyphosphate confers cadmium resistance in tobacco

Takeshi NAGATA, Tomoki KIMURA and Hidemitsu PAN-HOU

J Toxicol Sci. 2008 33(3) 371-373 


Genetic Engineering of Transgenic Tobacco for Enhanced Uptake and Bioaccumulation of Mercury

Takeshi NAGATA, Asako NAKAMURA, Toshifumi AKIZAWA and Hidemitsu PAN-HOU

Biological & Pharmaceutical Bulletin. 2009 32(9) 1491-1495


Chemical synthesis of N-acetylcysteine conjugates of bile acids and in vivo formation in cholestatic rats as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.

Mitamura K, Watanabe S, Sakai T, Okihara R, Sogabe M, Wakamiya T, Hofmann AF, Ikegawa S.

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 2009 Sep 1;877(25):2630-8


Production and characterization of a monoclonal antibody to capture proteins tagged with lithocholic acid

Ikegawa S, Yamamoto T, Miyashita T, Okihara R, Ishiwata S, Sakai T, Chong RH, Maeda M, Hofmann AF, Mitamura K.

Analytical Science. 2008 24(11);1475-80


Enzyme immunoassay of D-3-methoxy-4-hydroxyphenyl-glycol in human urines
K. Hirose, T. Akizawa, M. Konishi, A. Kakuyama, M. Yoshioka, Y. Andow, T. Hoshino
Biogenic Amines, 20, 202-212, 2006 

A screening system of prodrugs selective for MAO-A or MAO-B.

Matsukawa M, Hirai T, Karita S, Akizawa T, Pan-Hou H, Yoshioka M, Goto G, Parvez H, Youdim MB.

Neurotoxicology, 2004 Jan;25(1-2):293-302.