研究業績


Yoneda, K., Fujii, M., Imaoka, A., Kobayashi, R., Hayashi R., Yoshida, Y., Kohno, T., Tsuji, T.:Preventive effect of edaravone ointment on cyclophosphamide-chemotherapy induced alopecia．Support Care Cancer , doi: 10.1007/s00520-021-06189-7, Published online Apr. 2, 2021

Yoshida, Y., Mikami, N., Nakanishi, Y., Saimoto, M., Nagaike, A., Shimono, H., Nakano, S., Tsuji, T., Kohno, T.: Characterization of an Expanded IL-10-Producing-Suppressive T cell Population Associated with Immune Tolerance. Biol. Phar. Bull., doi:10.1248/bpb.b19-01072, Published online Jan. 26, 2021.

Hosoda, A., Matsumoto, Y., Toriyama, Y., Tsuji, T., Yoshida, Y., Masamichi S., Kohno, T.: Telmisartan Exacerbates Cisplatin-Induced Nephrotoxicity in a Mouse Model. Biol. Pharm. Bull., 43(9), 1331-1337, 2020.

Ogushi, S., Yoshida, Y., Nakanishi, T., Kimura, T.: CpG Site-Specific Regulation of Metallothionein-1 Gene Expression. Int J Mol Sci., doi:10.3390/ijms21175946, Published online Aug. 19, 2020.

吉田侑矢，河野武幸：免疫抑制薬フィンゴリモド（FTY720）を用いた免疫寛容誘導．臨床免疫・アレルギー科, 71(5), 508-514, 2019

Tsuji, T., Hattori, Y., Komori, K., Yoshida, Y., Banno, R., Kohno, T.: Intravenous Lipid Emulsion Therapy for Acute Clomipramine Intoxication in Rats. Acute Med. Surg., 5(3), 272-277, 2018.

大坪達弥，辻琢己，梅山貴生，首藤みほ，米須香那，松本美菜子，吉田侑矢，坂野理絵，友金幹視，藤田敦夫，河野武幸，三上正：ダカルバジン投与における血管痛対策の検討．YAKUGAKU ZASSHI, 137(3): 363-369, 2017.

Tsuji, T., Okuno, S., Kuroda, A., Hamazaki, J., Chikami, T., Sakurai, S., Yoshida, Y., Banno, R., Fujita, T., Kohno, T.: Therapeutic Approach to Mite-induced Intractable Dermatitis Using Novel Immunomodulator FTY720 Ointment (Fingolimod) in NC/Nga Mice. Allergol. Int., 65, 172-179, 2016.

Yoshida, Y., Mikami, N., Matsudhima, Y., Miyawaki, M., Endo, H., Banno, R., Tsuji, T., Fujita, T., Kohno, T.: Combination treatment with fingolimod and a pathogenic antigen prevents relapse of glucose-6-phosphate isomerase peptide-induced arthritis. Immunity,Inflammation and Disease,4(3), 263-273, 2016.

Yoshida, Y., Mikami, N., Matsushima, Y., Otani, F., Miyawaki, M., Takatsuji, M., Banno, R., Tsuji, T., Fujita, T., Tsujikawa, K., Kohno, T.: Functional Mechanism(s) of the Inhibition of Disease Progression by Combination Treatment with Fingolimod plus Pathogenic Antigen in a Glucose-6-phosphate Isomerase Peptide-Induced Arthritis Mouse Model. Biol. Pharm. Bull., 38(8), 1120-5, 2016.

Yoshida, Y., Mikami, N., Tsuji, T., Takada, Y., Nakazawa, Y., Dan, R., Takatsuji, M., Fujita, T., Tsujikawa, K., Kohno, T.: Mechanism of induction of immune tolerance in experimental autoimmune encephalomyelitis by combination treatment with Fingolimod (FTY720) plus pathogenic autoantugen. Clinical and Experimental Neuroimmunology, 6(1), 49-56, 2015.

辻 琢己, 大坪 達弥, 梅山 貴生, 首藤 みほ, 米須 香那, 松本 美菜子, 吉田 侑矢, 坂野 理絵, 三上 正, 河野 武幸 : ダカルバジン投与時に生じる血管痛の抑制を目的とした投与方法. YAKUGAKU ZASSHI, 134(9), 981-986, 2014.

Yoshida, Y., Tsuji, T., Watanabe, S., Matsushima, A., Matsushima, Y., et al.: Efficacy of Combination Treatment with Fingolimod (FTY720) plus Pathogenic Autoantigen in a Glucose-6-phosphate Isomerase Peptide (GPI325-339)-induced Arthritis Mouse Model. Biol. Pharm. Bull., 36(11), 1739-1746, 2013.

辻 琢己, 吉田 侑矢, 河野 武幸: フィジカルアセスメント実習は薬学生の意識を改変する．医学教育, 44(3), 121-131, 2013.

辻 琢己, 吉田 侑矢, 藤多 哲朗, 河野 武幸: ダニ抗原誘発性難治性皮膚炎に対する新規免疫調節薬FTY720とベタメタゾン軟膏併用療法の有用性 : NC/Ngaマウスを用いた検討. アレルギー, 61(7), 948-958, 2012.

栗尾 和佐子, 小西 元美, 奥野 智史, 中尾 晃幸, 辻 琢己, 山室 晶子, 吉田 侑矢, 山本 祐実, 西川 智絵, 安原 智久, 柳田 一夫, 中村 三孝, 曽根 知道, 河野 武幸, 荻田 喜代一, 前田 定秋: 自己研鑽・参加型キャリア形成教育プログラム:｢薬系インターンシップ・ボランティア体験実習｣とその成果. 医療薬学, 38(12), 757-766, 2012.

Tsuji, T., Yoshida, Y., Iwatsuki, R., Inoue, M., Fujita, T., Kohno T.: Therapeutic Approach to Steroid-Resistant Dermatitis Using Novel Immunomodulator FTY720(Fingolimod) in Combination with Betamethasone Ointment in NC/Nga Mice. Biol. Pharm. Bull., 35(8), 1314-1319, 2012.

Tsuji, T., Yoshida, Y., Fujita, T., Kohono, T.: Oral therapy for type 1 diabetes mellitus using a novel immunomodulater, FTY720 (Fingolimod), in combination with sitagliptin, a dipeptidyl peptidase-4 inhibitor, examined in non-obese diabetic(NOD) mice. J. Diab. Invest., 3(5), 441-448, 2012.

吉田 侑矢, 辻 琢己, 細田 敦規, 河野 武幸, 久保 貞也, 佐竹 正人, 難波 洋, 瀬野 智美, 前田 定秋: 実地臨床に従事する薬剤師参加型のセルフメディケーション演習の有用性. 医療薬学, 38(5), 288-298, 2012.

Tsuji, T., Inoue, M., Yoshida, Y., Fujita, T., Kaino, Y., Kohono, T.: Therapeutic approach for type-1 diabetes mellitus using a novel immunomodulator, FTY720(Fingolimod), in combination with once-daily injection of insulin glargine, examined in non-obese diabetic(NOD) mice. J. Diab. Invest., 3(2), 132-137, 2012.

Yoshida, Y., Tsuji, T., Fujita, T., Kohno, T.: Relapse of Experimental Autoimmune Encephalomyelitis (EAE) After Discontinuation of FTY720 (Fingolimod) Treatment, but not After Combination of FTY720 and Pathogenic Autoantigen. Biol. Pharm. Bull., 34(6), 933-936, 2011.

Yoshida, Y., Iwatsuki, R., Hakobe, H., Higuchi, S., Yoshimura, K., Yonemura, T., Tsuji, T., Kohno, T.,Hayashi, M., Fujita, T.: Effectiveness of A Novel Immunomodulator, FTY720 (Fingolimod) , on Autoimmune Neurological Disorders. Clin. Pharmacol. Ther., 21, 81-89, 2011.

Tsuji, T., Kato, Y., Mitsui, K., Nakatani, F., Watanabe, K., Yoshida, Y., Kohno, T., Fujita, T.: Effectiveness of A Novel Immunomodulator, FTY720 (Fingolimod) , on Atopic Dermatitis. Clin. Pharmacol. Ther., 21, 75-79, 2011.

Tsuji, T., Inoue, M., Otsuka, G., Matsuda, Y.,Yara, T., Watanabe, Y., Yoshida, Y., Kohno, T., Kaino, Y., Fujita, T.: Effectiveness of A Novel Immunomodulator, FTY720 (Fingolimod) , on Type-1 Diabetes Mellitus. Clin. Pharmacol. Ther., 21, 69-74, 2011.

田中 祥之, 岡野 由貴, 吉田 侑矢, 辻 琢己, 河野 武幸: イムノアッセイによるセラペプターゼの定量法開発とバリデーション. 生物試料分析, 33, 260-266, 2010.