1. Yusuke Tanaka, Rikuto Fukaishi, Daiki Okamoto, Takanori Kurakazu, Tokio Nakai, Haruya Yagi, Shinji Sakuma. Impact of Composition of Lipid-Based Formulations on First-Pass Drug Metabolism after Oral Administration, Mol. Pharmaceutics, in press.
2. Yusuke Tanaka, Hinata Arai, Aya Hidaka, Saki Noda, Ko Imai, Fumiya Tsujisawa, Haruya Yagi, Shinji Sakuma, In Vitro Digestion–In Situ Absorption Setup Employing a Physiologically Relevant Value of the Membrane Surface Area/Volume Ratio for Evaluating Performance of Lipid-Based Formulations: A Comparative Study with an In Vitro Digestion–Permeation Model, Mol. Pharmaceutics., 21 (2024) 3459-3470.
3. 山田玄，早川佳代子，田中佑典，佐藤ルブナ，浜田幸宏，櫻井彩奈，山元佳，熊埜御堂雄大，坂本龍司，森嶋康之，大曲貴夫. アルベンダゾールの血中濃度測定を行った多包性エキノコックス症の一例. 感染症学雑誌. 98 (2024) 301-305.
4. Nobuhiro Mori, Keisuke Oda, Hideki Takakura, Yusuke Tanaka, Tomoharu Yokooji, Teruo Murakami. Comparison of Berberine Bioavailability between Oral and Rectal Administrations in Rats. Biol. Pharm. Bull. 46 (2023) 1639-1642.
5. Yusuke Tanaka, Kazuhiro Ito, Takanori Kurakazu, Satoshi Kasaoka, Separate evaluation of fraction absorbed and intestinal availability after oral administration of drugs based on the measurement of portal and systemic plasma concentrations and luminal concentration, Mol. Pharmaceutics, 20 (2023) 1933-1941.
6. Yusuke Tanaka, Hirotaka Doi, Takeru Katano, Satoshi Kasaoka, The impact of quantity of lipid based formulations with different compositions on the oral absorption of ritonavir: A trade-off between apparent solubility and permeability, Eur. J. Pharm. Sci., 168 (2022) 106079.
7. Yusuke Tanaka, Taiki Harada, Kazuhiro Ito, Takanori Kurakazu, Satoshi Kasaoka, Intraluminal behavior of various transporter substrates in rat gastrointestinal tract, J. Pharm. Pharm. Sci, 24 (2021) 563-570.
8. Yusuke Tanaka, Tri-Hung Nguyen, Estelle J.A. Suys, Christopher J.H. Porter, Digestion of lipid-based formulations not only mediates changes to absorption of poorly soluble drugs due to differences in solubilisation, but also reflects changes to thermodynamic activity and permeability, Mol. Pharmaceutics, 18 (2021) 1768-1778.
9. Yusuke Tanaka, Hirotaka Doi, Takeru Katano, Satoshi Kasaoka, Effects of lipid digestion and drug permeation/re-dissolution on absorption of orally administered ritonavir as different lipid-based formulations, Eur. J. Pharm. Sci., 157 (2021) 105604.
10. Yusuke Tanaka, Haruki Higashino, Makoto Kataoka, Shinji Yamashita, In vivo fluid volume in rat gastrointestinal tract: kinetic analysis on the luminal concentration of non-absorbable FITC-dextran after oral administration, J. Pharm. Sci., 109 (2020) 1863-1866.
11. Yusuke Tanaka, Erin Tay, Tri-Hung Nguyen, Christopher J.H. Porter, Quantifying in vivo luminal drug solubilization/precipitation profiles to explain the performance of lipid based formulations, Pharm. Res., 37 (2020) 47.
12. Yusuke Tanaka, Risa Matsubara, Kana Furukawa, Seira Satonaka, Saroshi Kasaoka, The influence of viscosity-enhancing agents on oral absorption of drugs, Pharmazie. 74 (2019) 661-664
13. Yushi Sunazuka, Keisuke Ueda, Kenjirou Higashi, Yusuke Tanaka, Kunikazu Moribe, Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate, Int. J. Pharm., 546 (2018) 263-271.
14. Yusuke Tanaka, Masahisa Sugihara, Ayaka Kawakami, So Imai, Takafumi Itou, Hirokazu Murase, Kazunori Saiki, Satoshi Kasaoka, Hiroshi Yoshikawa, In vivo analysis of supersaturation/precipitation/absorption behavior after oral administration of pioglitazone hydrochloride salt; determinant site of oral absorption, Eur. J. Pharm. Sci., 106 (2017) 431-438.
15. Yusuke Tanaka, Ayaka Kawakami, Ami Nanimatsu, Misaki Horio, Jumpei Matsuoka, Takami Wada, Satoshi Kasaoka, Hiroshi Yoshikawa, In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of oral absorption, Eur. J. Pharm. Sci. 1 (2017) 464-471.
16. Yusuke Tanaka, Atsuo Kubota, Akira Matsuo, Ayaka Kawakami, Hiroki Kamizi, Akane Mochigoe, Takahiro Hiramachi, Satoshi Kasaoka, Hiroshi Yoshikawa, Shunji Nagata, Effect of absorption behavior of solubilizers on drug dissolution in the gastrointestinal tract: Evaluation based on in vivo luminal concentration-time profile of cilostazol, a poorly soluble drug, and solubilizers, J. Pharm. Sci., 105 (2016) 2825-31.
17. Yusuke Tanaka, Takanori Goto, Makoto Kataoka, Shinji Sakuma, Shinji Yamashita, Impact of luminal fluid volume on the drug absorption after oral administration: Analysis based on in vivo drug concentration-time profile in the gastrointestinal tract, J. Pharm. Sci., 104 (2015) 3120-7.
18. Yusuke Tanaka, Toshiyuki Baba, Koji Tagawa, Ryoichi Waki, Shunji Nagata, Prediction of oral absorption of low-solubility drugs by using rat simulated gastrointestinal fluids: the importance of regional differences in membrane permeability and solubility, J. Pharm. Pharm. Sci., 17 (2014) 106-20.
19. Yusuke Tanaka, Hiroko Ueyama, Masaomi Ogata, Takakazu Daikoku, Masatoyo Morimoto, Akitsugu Kitagawa, Yuji Imajo, Takashi Tahara, Mitsugi Inkyo, Noriyuki Yamaguchi, Shunji Nagata, Evaluation of nanodispersion of iron oxides using various polymers, Ind. J. Pharm. Sci., 76 (2014) 54-61.
20. Yusuke Tanaka, Ryoichi Waki, Shunji Nagata, Species differences in the dissolution and absorption of griseofulvin and albendazole, Biopharmaceutics Classification System class II drugs, in the gastrointestinal tract. Drug Metab. Pharmacokinet., 28 (2013) 485-90.
21. Shunji Nagata, Aya Jin-nai, Ken-ichi Hirai, Mikako Baba, Kousuke Higashi, Yusuke Tanaka, Evaluation of dissolution of osmotic-controlled release paliperidone tablets using the reciprocating cylinder method, Yakugaku Zasshi, 133 (2013) 405-10.
22. Yusuke Tanaka, Toshihiro Hara, Ryoichi Waki, Shunji Nagata, Regional differences in the components of luminal water from rat gastrointestinal tract and comparison with other species, J. Pharm. Pharm. Sci., 15 (2012) 510-518.
23. Yusuke Tanaka, Mitsugi Inkyo, Ryoko Yumoto, Junya Nagai, Mikihisa Takano, Shunji Nagata, Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption, Drug Dev. Ind. Pharm., 38 (2012) 1015-23.
24. Yusuke Tanaka, Mitsugi Inkyo, Ryoko Yumoto, Junya Nagai, Mikihisa Takano, Shunji Nagata, Evaluation of in vitro dissolution and in vivo oral absorption of drug nanopowders prepared by novel wet-milling equipment, Current Nanoscience, 6 (2010) 571-576.
25. Yusuke Tanaka, Mitsugi Inkyo, Ryoko Yumoto, Junya Nagai, Mikihisa Takano, Shunji Nagata, Nanoparticulation of poorly water soluble drugs using a wet-mill process and physicochemical properties of the nanopowders. Chem. Pharm. Bull, 57 (2009) 1050-7.
26. Yoshie Masaoka, Yusuke Tanaka, Makoto Kataoka, Shinji Sakuma, Shinji Yamashita, Site of drug absorption after oral administration: Assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract. Eur. J. Pharm. Sci. 29 (2006) 240-50.

1. 田中佑典, 脂質分散製剤からの薬物の消化管吸収機構の解明および吸収性予測法の開発, 薬学雑誌, 143 (2023) 721-727.
2. 田中佑典,脂質分散製剤経口投与後の薬物過飽和溶解/吸収挙動の評価, 永井記念薬学国際交流財団年報, 25 (2019) 30-32.
3. 長田俊治、伊波綾乃、竹下亜沙未、東昂佑、馬場実佳子、田中佑典, 溶出試験液中で不安定な薬物の溶出試験方法, 医学と薬学, 75 (2018) 1051-1060.
4. 田中佑典, 消化管内における難溶解性薬物の過飽和溶解挙動の評価, Pharm Stage, 17 (2017) 25-28.
5. 長田俊治，田中佑典，市場泰全，前田賴伸，日浦和徳，大塚幸三, 地域連携による医薬品の品質保証, Pharm Tech Japan, 31 (2015) 51-54.
6. 田中佑典, 難溶解性薬物の消化管内溶解性・吸収性の部位差と種差, 薬剤学, 74 (2014) 197-201.
7. 田中佑典, 錠剤の崩壊性に及ぼす水分子の動きやすさの影響, ファルマシア, 50 (2014) 349.

ページトップへ